Clinical Effectiveness of SARS-CoV-2 Booster Vaccine Against Omicron Infection in Residents and Staff of Long-term Care Facilities: A Prospective Cohort Study (VIVALDI).

Oliver T StirrupMadhumita ShrotriNatalie L AdamsMaria KrutikovHadjer Nacer-LaidiBorscha AzmiTom PalmerChristopher FullerAidan Irwin-SingerVerity BayntonGokhan TutPaul MossAndrew HaywardAndrew CopasLaura J Shallcross

Published in: Open forum infectious diseases (2022)

Our findings suggest that booster vaccination provided sustained protection against severe outcomes following infection with the Omicron variant, but no protection against infection from 4 months onwards. Ongoing surveillance for SARS-CoV-2 in LTCFs is crucial.

Keyphrases

sars cov
long term care
respiratory syndrome coronavirus
randomized controlled trial
systematic review
public health