Computationally inferred cell-type specific epigenome-wide DNA methylation analysis unveils distinct methylation patterns among immune cells for HIV infection in three cohorts.

Xinyu ZhangYing HuRal E VandenhoudtChunhua YanVincent C MarconiMardge H CohenZuoheng WangAmy C JusticeBradley E AouizeratKe Xu

Published in: PLoS pathogens (2024)

Our findings uncovered computationally inferred cell-type specific modifications in the host epigenome for people with HIV that contribute to the growing body of evidence regarding HIV pathogenesis.

Keyphrases

dna methylation
antiretroviral therapy
hiv positive
hiv infected
genome wide
human immunodeficiency virus
hiv testing
hiv aids
gene expression
hepatitis c virus
men who have sex with men
copy number
south africa