Measuring health-related quality of life in children with suspected genetic conditions: validation of the PedsQL proxy-report versions.

Hadley Stevens SmithMichael LeoKatrina GoddardKristin MuessigFrank AngeloSara KnightSimon OutramNicole R KellyChristine Rini

Published in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2024)

The PedsQL Generic Core Scales and Infant Scales may be appropriate to measure HRQoL in pediatric patients with suspected genetic conditions across a wide age range. While we found evidence of acceptable internal consistency and preliminary convergent validity in this sample, there were some potential problems with structural validity and reliability that require further attention.

Keyphrases

genome wide
mental health
copy number
young adults
working memory
pulmonary embolism
human health
childhood cancer