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The influence of drugs on peripheral nerve regeneration.

Olimpiu BotaLucian Fodor
Published in: Drug metabolism reviews (2019)
Currently, there are no established adjuvant drugs for the acceleration of peripheral nerve regeneration. In this paper, we reviewed the literature from the last 10 years and described the drugs proved to accelerate the functional and histological regeneration of the peripheral nerves, either after trauma or in neuropathy experimental models. The vast majority of the studies were experimental with very few small clinical studies, which indicates the need for prospective randomized studies to identify the best drugs to use as adjuvants for nerve regeneration.
Keyphrases
  • peripheral nerve
  • stem cells
  • systematic review
  • wound healing
  • early stage
  • open label
  • randomized controlled trial
  • drug induced
  • placebo controlled