αVβ3 Integrin regulates astrocyte reactivity.

Raúl Lagos-CabréAlvaro AlvarezMilene KongFrancesca Burgos-BravoAreli CárdenasEdgardo Rojas-MancillaRamón Pérez-NuñezRodrigo Herrera-MolinaFabiola RojasPascal SchneiderMario Herrera-MarschitzAndrew F G QuestBrigitte van ZundertLisette Leyton

Published in: Journal of neuroinflammation (2017)

Therefore, inflammation induces expression of αVβ3 Integrin and other proteins, astrocyte reactivity, and Thy-1 responsiveness. Importantly, ectopic control of β3 Integrin levels modulates these responses regardless of inflammation.

Keyphrases

oxidative stress
cell adhesion
poor prognosis
cell migration
binding protein