Clinical evaluation of the effectiveness of fusion-induced asymmetric transcription assay-based reverse transcription droplet digital PCR for ALK detection in formalin-fixed paraffin-embedded samples from lung cancer.
Yuanyuan LiuShafei WuXiaohua ShiLinping LuLingxiang ZhuYong GuoLi ZhangXuan ZengPublished in: Thoracic cancer (2020)
An absolute quantitative FIATA-based RT-ddPCR was developed and validated for ALK fusion detection in NSCLC. This method can rapidly, accurately, and objectively classify ALK types and help with individual therapy.
Keyphrases
- advanced non small cell lung cancer
- clinical evaluation
- real time pcr
- high throughput
- loop mediated isothermal amplification
- small cell lung cancer
- transcription factor
- randomized controlled trial
- label free
- physical activity
- epidermal growth factor receptor
- systematic review
- high glucose
- high resolution
- diabetic rats
- single cell
- oxidative stress
- endothelial cells
- drug induced
- solid state
- cell therapy