Affective Symptoms in Pregnancy are Associated with the Vaginal Microbiome.

Kristin ScheibleRobert BeblavyMichael B SohnXing QuiAnn L GillJaniret Narvaez-MirandaJessica BrunnerRichard K MillerEmily S BarrettTom G O'ConnorSteven R Gill

Published in: bioRxiv : the preprint server for biology (2024)

Prenatal affective symptoms and stress are associated with maternal, obstetric, and child health outcomes, but the mechanisms underlying these links and their application to intervention remain unclear. The findings from this investigation extend prior microbiome-oriented research by demonstrating that the maternal vaginal microbiome composition has a biologically plausible mechanistic link with affective symptoms that also suggest additional clinical applications for assessment and intervention.

Keyphrases

bipolar disorder
pregnancy outcomes
randomized controlled trial
pregnant women
sleep quality
birth weight
preterm birth
type diabetes
stress induced