Endovascular Therapy for Acute Stroke with a Large Ischemic Region.
Shinichi YoshimuraNobuyuki SakaiHiroshi YamagamiKazutaka UchidaMikiya BeppuKazunori ToyodaYuji MatsumaruYasushi MatsumotoKazumi KimuraMasataka TakeuchiYukako YazawaNaoto KimuraKeigo ShigetaHirotoshi ImamuraIchiro SuzukiYukiko EnomotoSo TokunagaKenichi MoritaFumihiro SakakibaraNorito KinjoTakuya SaitoReiichi IshikuraManabu InoueTakeshi MorimotoPublished in: The New England journal of medicine (2022)
In a trial conducted in Japan, patients with large cerebral infarctions had better functional outcomes with endovascular therapy than with medical care alone but had more intracranial hemorrhages. (Funded by Mihara Cerebrovascular Disorder Research Promotion Fund and the Japanese Society for Neuroendovascular Therapy; RESCUE-Japan LIMIT ClinicalTrials.gov number, NCT03702413.).