Intravoxel incoherent motion diffusion-weighted MRI for the characterization of inflammation in chronic liver disease.

Thierry LefebvreMélanie HébertLaurent BilodeauGiada SebastianiMilena CernyDamien OliviéZu-Hua GaoMarie-Pierre SylvestreGuy CloutierBich N NguyenGuillaume GilbertAn Tang

Published in: European radiology (2020)

• IVIM parameters derived from DWI series with 10 b-values are reproducible for liver tissue characterization. • This retrospective two-center study showed that perfusion fraction provided good diagnostic performance for distinguishing dichotomized grades of inflammation. • Fibrosis is a significant confounder on the association between inflammation and perfusion fraction.

Keyphrases

diffusion weighted
contrast enhanced
magnetic resonance imaging
diffusion weighted imaging
oxidative stress
magnetic resonance
computed tomography
cross sectional
drug induced