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Corroborating evidence for aberrant expression of histone deacetylase 8 in endometriosis.

Hanxi ZhengXishi LiuSun-Wei Guo
Published in: Reproductive medicine and biology (2023)
Hdac8 is progressively and aberrantly overexpressed as endometriotic lesions progress. This, along with the documented HDAC1 upregulation in endometriosis and the overwhelming evidence for the therapeutic potentials of HDACIs, calls for further and in-depth investigation of epigenetic aberrations of endometriosis in general and of HDACs in particular.
Keyphrases
  • histone deacetylase
  • poor prognosis
  • dna methylation
  • optical coherence tomography
  • long non coding rna
  • signaling pathway
  • copy number