The Landscape of BRCA Mutations among Egyptian Women with Breast Cancer.
Hamdy A AzimSamah A LoutfyHatem A AzimNermin S KamalNasra F Abdel FattahMostafa H ElberryMohamed R AbdelazizMarwa AbdelsalamMadonna AzizKyrillus S ShohdyLoay KassemPublished in: Oncology and therapy (2023)
The reported prevalence was highly variable among the small-sized published studies that adopted adequate techniques. In our patient cohort, there was a high incidence of VUS in BRCA1/2 genes. Accordingly, there is an actual demand to conduct a prospective well-designed national study to accurately estimate the prevalence of BRCA1/2 mutations among patients with BC in Egypt.