Age-Dependent Effects of Voluntary Wheel Running Exercise on Voiding Behavior and Potential Age-Related Molecular Mechanisms in Mice.

Teresa T LiuLaura E PascalScott R Bauer Hannah N MilesJules B PankseppGranville L LloydLingjun LiDonald B DeFrancoWilliam A Ricke

Published in: The journals of gerontology. Series A, Biological sciences and medical sciences (2024)

Voluntary aerobic exercise improves voiding behavior, mobility, and decreases prostatic mitochondrial protein expression and inflammation in aged mice. This promising model could be used to evaluate molecular mechanisms of aerobic exercise as a novel lifestyle intervention for older men with LUTS/BPH.

Keyphrases

benign prostatic hyperplasia
lower urinary tract symptoms
physical activity
oxidative stress
high fat diet induced
high intensity
randomized controlled trial
middle aged
metabolic syndrome
cardiovascular disease
prostate cancer
wild type
resistance training
adipose tissue
climate change
risk assessment