Serial Nigrostriatal Dopaminergic Imaging in Mild Cognitive Impairment With Lewy Bodies, Alzheimer Disease, and Age-Matched Controls.
Rory DurcanGemma RobertsCalum Alexander HamiltonPaul C DonaghyKim HoweSean J CollobyLouise M AllanMichael FirbankSarah LawleyGeorge S PetridesJim J LloydJohn-Paul TaylorJohn T O'BrienAlan J ThomasPublished in: Neurology (2023)
This study provides Class II evidence that longitudinal declines in striatal uptake measured via 123[I]-FP-CIT SPECT are associated with mild cognitive impairment (MCI) due to Lewy body disease but not MCI due to Alzheimer disease.