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Serial Nigrostriatal Dopaminergic Imaging in Mild Cognitive Impairment With Lewy Bodies, Alzheimer Disease, and Age-Matched Controls.

Rory DurcanGemma RobertsCalum Alexander HamiltonPaul C DonaghyKim HoweSean J CollobyLouise M AllanMichael FirbankSarah LawleyGeorge S PetridesJim J LloydJohn-Paul TaylorJohn T O'BrienAlan J Thomas
Published in: Neurology (2023)
This study provides Class II evidence that longitudinal declines in striatal uptake measured via 123[I]-FP-CIT SPECT are associated with mild cognitive impairment (MCI) due to Lewy body disease but not MCI due to Alzheimer disease.
Keyphrases
  • mild cognitive impairment
  • cognitive decline
  • parkinson disease
  • high resolution
  • deep brain stimulation
  • cross sectional
  • pet ct