Convalescent Plasma Antibody Levels and the Risk of Death from Covid-19.
Michael J JoynerRickey E CarterJonathon W SenefeldStephen A KlassenJohn R MillsPatrick W JohnsonElitza S TheelChad C WigginsKatelyn A BrunoAllan M KlompasElizabeth R LesserKatie L KunzeMatthew A SextonJuan C Diaz SotoSarah E BakerJohn R A ShepherdNoud van HelmondNicole C VerdunPeter W MarksCamille M van BuskirkJeffrey L WintersJames R StubbsRobert F ReaDavid O HodgeVitaly HerasevichEmily R WhelanAndrew J ClayburnKathryn F LarsonJuan G RipollKylie J AndersenMatthew R BurasMatthew N P VogtJoshua J DennisRiley J RegimbalPhilippe R BauerJanis E BlairNigel S PanethDeLisa FairweatherR Scott WrightArturo CasadevallPublished in: The New England journal of medicine (2021)
Among patients hospitalized with Covid-19 who were not receiving mechanical ventilation, transfusion of plasma with higher anti-SARS-CoV-2 IgG antibody levels was associated with a lower risk of death than transfusion of plasma with lower antibody levels. (Funded by the Department of Health and Human Services and others; ClinicalTrials.gov number, NCT04338360.).
Keyphrases
- sars cov
- mechanical ventilation
- coronavirus disease
- healthcare
- respiratory syndrome coronavirus
- cardiac surgery
- acute respiratory distress syndrome
- mental health
- endothelial cells
- intensive care unit
- primary care
- public health
- sickle cell disease
- health information
- respiratory failure
- induced pluripotent stem cells
- acute kidney injury
- risk assessment
- extracorporeal membrane oxygenation
- social media
- climate change
- pluripotent stem cells