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Regeneration of pulp-dentin complex using human stem cells of the apical papilla: in vivo interaction with two bioactive materials.

Diana B SequeiraAna Rafaela OliveiraCatarina M SeabraPaulo J PalmaCarlos RamosMaria H FigueiredoAna C SantosAna L CardosoJoão PeçaJoão Miguel Marques Santos
Published in: Clinical oral investigations (2021)
SCAPs offer a viable alternative to other dental stem cells (DSCs) in their regenerative properties when enclosed in the microenvironment of human tooth roots. The present study also suggests that the presence of bioactive materials does not hinder or impede the formation of new hard tissues, but the presence of Biodentine may promote greater mineralized tissue deposition.
Keyphrases
  • stem cells
  • endothelial cells
  • cell therapy
  • induced pluripotent stem cells
  • pluripotent stem cells
  • gene expression
  • mesenchymal stem cells
  • tissue engineering
  • bone regeneration