Effects of caffeine, methylliberine, and theacrine on vigilance, marksmanship, and hemodynamic responses in tactical personnel: a double-blind, randomized, placebo-controlled trial.

Harry P Cintineo Marissa L Bello Alexa J Chandler Thomas D Cardaci Bridget A McFadden Shawn M Arent

Published in: Journal of the International Society of Sports Nutrition (2022)

These findings suggest similar benefits on RT during a vigilance task between CAF, containing 300 mg caffeine, and CMT above PLA, though CAF resulted in slightly less favorable hemodynamic changes. This study is the first to provide data showing similar efficacy of combined caffeine, methylliberine, and theacrine compared to double the caffeine dose consumed alone on vigilance RT but without a significant rise in DBP above PLA in tactical personnel.

Keyphrases

double blind
open label
clinical trial
randomized controlled trial
electronic health record
study protocol
big data
machine learning
data analysis