The relationship between sperm nuclear DNA fragmentation, mitochondrial DNA fragmentation, and copy number in normal and abnormal human ejaculates.
Ana TímermansFátima OteroManuel GarridoJaime GosálvezStephen D JohnstonJosé Luis Fernández GarcíaPublished in: Andrology (2023)
High-quality ejaculates show lower nuclear SDF and retain less mtDNA copies, with approximately half of them fragmented, so that the absolute number of non-fragmented mtDNA molecules per spermatozoon is extremely low.