Damage-induced pyroptosis drives endogenous thymic regeneration via induction of Foxn1 by purinergic receptor activation.
Sinéad KinsellaCindy A EvandyKirsten CooperAntonella CardinaleLorenzo IovinoPaul deRoosKayla S HopwoColton W SmithDavid GranadierLucas B SullivanEnrico VelardiJarrod A DudakovPublished in: bioRxiv : the preprint server for biology (2023)
expression in cTECs via activation of P2Y2 Therapeutic targeting of the P2Y2 receptor promotes thymic regeneration.