Semiquantitative assessment of phosphatase and tensin homolog value with immunohistochemistry in colorectal cancer.

Wifanto Saditya JeoToar J M LalisangNurjati C SiregarAru W SudoyoTrevino PakasiSri W JusmanAsmarinah Asmarinah

Published in: The International journal of biological markers (2024)

Semiquantitative assessment with cell counting multiplied by color intensity is a good method in determining PTEN expression. The use of immunohistochemical staining intensity and cell scoring with ROC cut-off is effective to elaborate the effects of PTEN in colorectal cancer (PTEN value > 199.0 was classified as strong and ≤ 199.0 as weak).

Keyphrases

cell proliferation
pi k akt
single cell
cell therapy
poor prognosis
high intensity
signaling pathway
bone marrow
protein kinase