Pharmacogene Variation in Thai Plasmodium vivax Relapse Patients Treated with a Combination of Primaquine and Chloroquine.

Monpat Chamnanphon Andrea GaedigkApichaya PuangpetchEkawat PasomsubWasun ChantratitaRhea J LongleyJetsumon SattabongkotPajaree ChariyavilaskulChonlaphat Sukasem

Published in: Pharmacogenomics and personalized medicine (2020)

Decreased activity of CYP2C19, ABCG2 and UGT2B7 in combination with CYP2D6 intermediate or poor metabolizer status may expose patients to a higher risk of Plasmodium vivax relapse. Further investigations are warranted to substantiate these findings.

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
peritoneal dialysis
prognostic factors
free survival