Andrea Gaedigk

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 50

Top Topics

Attention Deficit Hyperactivity Disorder

Metastatic Colorectal Cancer

Clinical Practice

Genome Wide Association Study

Top Venues

Clinical and translational science

Clinical pharmacology and therapeutics

Pharmacogenomics

This page only lists publications with an associated author ORCID identifier.

Publications

Jonathan B Wagner, Susan Abdel-Rahman, Geetha Raghuveer, Andrea Gaedigk, Erin C Boone, Roger Gaedigk, Vincent S Staggs, Gregory A Reed, Na Zhang, James Steven Leeder
SLCO1B1 Genetic Variation Influence on Atorvastatin Systemic Exposure in Pediatric Hypercholesterolemia. Genes 15 (1) (2024)
Julio D Duarte, Cameron D Thomas, And Craig R Lee, Rachel Huddart, José A G Agúndez, Jordan F Baye, Andrea Gaedigk, Teri E Klein, David E Lanfear, Andrew A Monte, Mohamed Nagy, Matthias Schwab, C Michael Stein, Chakradhara Rao Satyanarayana Uppugunduri, Ron H N van Schaik, Roseann S Donnelly, Kelly E Caudle, Jasmine A Luzum
Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2D6, ADRB1, ADRB2, ADRA2C, GRK4, and GRK5 Genotypes and Beta-Blocker Therapy. Clinical pharmacology and therapeutics (2024)
Kathryn E Kyler, Andrea Gaedigk, Susan M Abdel-Rahman, Vincent S Staggs, Robin E Pearce, Paul Toren, James Steven Leeder, Valentina Shakhnovich
Influence of novel CYP2C-haplotype on proton pump inhibitor pharmacokinetics in children. Clinical and translational science 17 (4) (2024)
Jonathan B Wagner, Susan Abdel-Rahman, Geetha Raghuveer, Andrea Gaedigk, Erin C Boone, Roger Gaedigk, Vincent S Staggs, Gregory A Reed, Na Zhang, James Steven Leeder
SLCO1B1 Genetic Variation Influence on Atorvastatin Systemic Exposure in Pediatric Hypercholesterolemia. Genes 15 (1) (2024)
Andrea Gaedigk, Amy J Turner, Cyrine E Haidar, Philip E Empey, Steven M Offer
Response to "DPYD genotyping panels: Impact of population diversity". Clinical and translational science 17 (4) (2024)
Katherine M Robinson, Seenae Eum, Zeruesenay Desta, Rachel Fynvola Tyndale, Andrea Gaedigk, Richard C Crist, Cyrine E Haidar, Alan L Myers, Caroline Flora Samer, Andrew Alexander Somogyi, Pablo Zubiaur, Otito F Iwuchukwu, Michelle Whirl-Carrillo, Teri E Klein, Kelly E Caudle, Roseann S Donnelly, Evan D Kharasch
Clinical Pharmacogenetics Implementation Consortium Guideline for CYP2B6 Genotype and Methadone Therapy. Clinical pharmacology and therapeutics (2024)
Julio D Duarte, Cameron D Thomas, And Craig R Lee, Rachel Huddart, José A G Agúndez, Jordan F Baye, Andrea Gaedigk, Teri E Klein, David E Lanfear, Andrew A Monte, Mohamed Nagy, Matthias Schwab, C Michael Stein, Chakradhara Rao Satyanarayana Uppugunduri, Ron H N van Schaik, Roseann S Donnelly, Kelly E Caudle, Jasmine A Luzum
Clinical Pharmacogenetics Implementation Consortium Guideline (CPIC) for CYP2D6, ADRB1, ADRB2, ADRA2C, GRK4, and GRK5 Genotypes and Beta-Blocker Therapy. Clinical pharmacology and therapeutics (2024)
Jonathan B Wagner, Susan Abdel-Rahman, Geetha Raghuveer, Andrea Gaedigk, Erin C Boone, Roger Gaedigk, Vincent S Staggs, Gregory A Reed, Na Zhang, James Steven Leeder
SLCO1B1 Genetic Variation Influence on Atorvastatin Systemic Exposure in Pediatric Hypercholesterolemia. Genes 15 (1) (2024)
Pablo Zubiaur, Cristina Rodríguez-Antona, Erin C Boone, Ann K Daly, Evangelia-Eirini Tsermpini, Lubna Q Khasawneh, Katrin Sangkuhl, Jorge Duconge, Mariana Rodrigues Botton, Jessica Savieo, Charity Nofziger, Michelle Whirl-Carrillo, Teri E Klein, Andrea Gaedigk
PharmVar GeneFocus: CYP4F2. Clinical pharmacology and therapeutics (2024)
Amy J Turner, Cyrine E Haidar, Wenjian Yang, Erin C Boone, Steven M Offer, Philip E Empey, Andrew Haddad, Saba Tahir, Gunter Scharer, Ulrich Broeckel, Andrea Gaedigk
Updated DPYD HapB3 haplotype structure and implications for pharmacogenomic testing. Clinical and translational science 17 (1) (2024)
Kathryn E Kyler, Andrea Gaedigk, Susan M Abdel-Rahman, Vincent S Staggs, Robin E Pearce, Paul Toren, James Steven Leeder, Valentina Shakhnovich
Influence of novel CYP2C-haplotype on proton pump inhibitor pharmacokinetics in children. Clinical and translational science 17 (4) (2024)
Alec W R Langlois, Meghan J Chenoweth, David Twesigomwe, Giada Scantamburlo, Michelle Whirl-Carrillo, Katrin Sangkuhl, Teri E Klein, Charity Nofziger, Rachel Fynvola Tyndale, Andrea Gaedigk
PharmVar GeneFocus: CYP2A6. Clinical pharmacology and therapeutics (2024)
Amy J Turner, Cyrine E Haidar, Wenjian Yang, Erin C Boone, Steven M Offer, Philip E Empey, Andrew Haddad, Saba Tahir, Gunter Scharer, Ulrich Broeckel, Andrea Gaedigk
Updated DPYD HapB3 haplotype structure and implications for pharmacogenomic testing. Clinical and translational science 17 (1) (2024)
Amy J Turner, Cyrine E Haidar, Wenjian Yang, Erin C Boone, Steven M Offer, Philip E Empey, Andrew Haddad, Saba Tahir, Gunter Scharer, Ulrich Broeckel, Andrea Gaedigk
Updated DPYD HapB3 haplotype structure and implications for pharmacogenomic testing. Clinical and translational science 17 (1) (2024)
Jonathan B Wagner, Susan Abdel-Rahman, Geetha Raghuveer, Andrea Gaedigk, Erin C Boone, Roger Gaedigk, Vincent S Staggs, Gregory A Reed, Na Zhang, James Steven Leeder
SLCO1B1 Genetic Variation Influence on Atorvastatin Systemic Exposure in Pediatric Hypercholesterolemia. Genes 15 (1) (2024)
Jonathan B Wagner, Susan Abdel-Rahman, Geetha Raghuveer, Andrea Gaedigk, Erin C Boone, Roger Gaedigk, Vincent S Staggs, Gregory A Reed, Na Zhang, James Steven Leeder
SLCO1B1 Genetic Variation Influence on Atorvastatin Systemic Exposure in Pediatric Hypercholesterolemia. Genes 15 (1) (2024)
Kathryn E Kyler, Andrea Gaedigk, Susan M Abdel-Rahman, Vincent S Staggs, Robin E Pearce, Paul Toren, James Steven Leeder, Valentina Shakhnovich
Influence of novel CYP2C-haplotype on proton pump inhibitor pharmacokinetics in children. Clinical and translational science 17 (4) (2024)
Amy J Turner, Cyrine E Haidar, Wenjian Yang, Erin C Boone, Steven M Offer, Philip E Empey, Andrew Haddad, Saba Tahir, Gunter Scharer, Ulrich Broeckel, Andrea Gaedigk
Updated DPYD HapB3 haplotype structure and implications for pharmacogenomic testing. Clinical and translational science 17 (1) (2024)
Kathryn E Kyler, Andrea Gaedigk, Susan M Abdel-Rahman, Vincent S Staggs, Robin E Pearce, Paul Toren, James Steven Leeder, Valentina Shakhnovich
Influence of novel CYP2C-haplotype on proton pump inhibitor pharmacokinetics in children. Clinical and translational science 17 (4) (2024)
Oyinlade Kehinde, Laura B Ramsey, Andrea Gaedigk, Akinyemi Oni-Orisan
Advancing CYP2D6 Pharmacogenetics Through a Pharmacoequity Lens. Clinical pharmacology and therapeutics (2023)
Amy J Turner, Cyrine E Haidar, Wenjian Yang, Erin C Boone, Steven M Offer, Philip E Empey, Andrew Haddad, Saba Tahir, Gunter Scharer, Ulrich Broeckel, Andrea Gaedigk
Updated DPYD HapB3 haplotype structure and implications for pharmacogenomic testing. Clinical and translational science (2023)
Pablo Zubiaur, James Steven Leeder, Francisco Abad-Santos, Andrea Gaedigk
Response to "What is the Current Clinical Impact of the CYP2C:TG Haplotype?" Clinical pharmacology and therapeutics (2023)
Amy J Turner, Charity Nofziger, Bronwyn E Ramey, Reynold C Ly, Chad A Bousman, José A G Agúndez, Katrin Sangkuhl, Michelle Whirl-Carrillo, Simone Vanoni, Henry M Dunnenberger, Gualberto Ruano, Martin A Kennedy, Michael S Phillips, Houda Hachad, Teri E Klein, Ann M Moyer, Andrea Gaedigk
PharmVar Tutorial on CYP2D6 Structural Variation Testing and Recommendations on Reporting. Clinical pharmacology and therapeutics (2023)
Amy J Turner, Cyrine E Haidar, Wenjian Yang, Erin C Boone, Steven M Offer, Philip E Empey, Andrew Haddad, Saba Tahir, Gunter Scharer, Ulrich Broeckel, Andrea Gaedigk
Updated DPYD HapB3 haplotype structure and implications for pharmacogenomic testing. Clinical and translational science (2023)
Amy J Turner, Cyrine E Haidar, Wenjian Yang, Erin C Boone, Steven M Offer, Philip E Empey, Andrew Haddad, Saba Tahir, Gunter Scharer, Ulrich Broeckel, Andrea Gaedigk
Updated DPYD HapB3 haplotype structure and implications for pharmacogenomic testing. Clinical and translational science (2023)
Pablo Zubiaur, Paula Soria-Chacartegui, Erin C Boone, Bhagwat Prasad, Jean Dinh, Wendy Y Wang, Santiago Zugbi, Andrea Rodríguez-Lopez, Eva González-Iglesias, James Steven Leeder, Francisco Abad-Santos, Andrea Gaedigk
Impact of CYP2C:TG haplotype on CYP2C19 substrates clearance in vivo, protein content and in vitro activity. Clinical pharmacology and therapeutics (2023)
Chad A Bousman, James M Stevenson, Laura B Ramsey, Katrin Sangkuhl, J Kevin Hicks, Jeffrey A Mills, Ajeet B Singh, Gualberto Ruaño, Daniel J Mueller, Evangelia Eirini Tsermpini, Jacob T Brown, Gillian C Bell, James Steven Leeder, Andrea Gaedigk, Stuart A Scott, Teri E Klein, Kelly E Caudle, Jeffrey R Bishop
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6, CYP2C19, CYP2B6, SLC6A4, and HTR2A Genotypes and Serotonin Reuptake Inhibitor Antidepressants. Clinical pharmacology and therapeutics (2023)
Estee Y Cramer, Jacquelaine Bartlett, Ernest R Chan, Andrea Gaedigk, Arsene C Ratsimbasoa, Rajeev K Mehlotra, Scott M Williams, Peter A Zimmerman
Pharmacogenomic variation in the Malagasy population: implications for the antimalarial drug primaquine metabolism. Pharmacogenomics (2023)
Katherine Black, B Randall Brenn, Andrea Gaedigk, Jonathan P Wanderer, Sara L Van Driest
Pediatric CYP2D6 metabolizer status and post-tonsillectomy nausea and vomiting after ondansetron. Clinical and translational science (2022)
Sudeep D Sunthankar, Prince J Kannankeril, Andrea Gaedigk, Andrew E Radbill, Frank A Fish, Sara L Van Driest
Influence of CYP2D6 genetic variation on adverse events with propafenone in the pediatric and young adult population. Clinical and translational science 15 (7) (2022)
Laura B Ramsey, Li Gong, Seung-Been Lee, Jonathan B Wagner, Xujia Zhou, Katrin Sangkuhl, Solomon M Adams, Robert J Straka, Philip E Empey, Erin C Boone, Teri E Klein, Mikko Niemi, Andrea Gaedigk
PharmVar GeneFocus: SLCO1B1. Clinical pharmacology and therapeutics (2022)
Wendy Y Wang, David Twesigomwe, Charity Nofziger, Amy J Turner, Lena-Sophie Helmecke, Ulrich Broeckel, Ashley D Derezinski, Scott Hazelhurst, Andrea Gaedigk
Characterization of Novel CYP2D6 Alleles across Sub-Saharan African Populations. Journal of personalized medicine 12 (10) (2022)
María Celsa Peña-Martín, Belén García-Berrocal, Almudena Sánchez-Martín, Elena Marcos-Vadillo, María Jesús García-Salgado, Santiago Sánchez, Carolina Lorenzo, David González-Parra, Francisco Sans, Manuel Franco, Andrea Gaedigk, María José Mateos-Sexmero, Catalina Sanz, María Isidoro-García
Ten Years of Experience Support Pharmacogenetic Testing to Guide Individualized Drug Therapy. Pharmaceutics 14 (1) (2022)
James Steven Leeder, Andrea Gaedigk, Krista J Wright, Vincent S Staggs, Sarah E Soden, Yvonne S Lin, Robin E Pearce
A longitudinal study of cytochrome P450 2D6 (CYP2D6) activity during adolescence. Clinical and translational science 15 (10) (2022)
Ernest Ricky Chan, Rajeev K Mehlotra, Karim A Pirani, Arsene C Ratsimbasoa, Scott M Williams, Andrea Gaedigk, Peter A Zimmerman
CYP2D6 gene resequencing in the Malagasy, a population at the crossroads between Asia and Africa: a pilot study. Pharmacogenomics 23 (5) (2022)
Pablo Zubiaur, Andrea Gaedigk
CYP2C18: the orphan in the CYP2C family. Pharmacogenomics 23 (17) (2022)
Monpat Chamnanphon, Rattanaporn Sukprasong, Andrea Gaedigk, Weerawat Manosuthi, Pajaree Chariyavilaskul, Supeecha Wittayalertpanya, Napatrupron Koomdee, Thawinee Jantararoungtong, Apichaya Puangpetch, Chonlaphat Sukasem
Influence of SULT1A1*2 Polymorphism on Plasma Efavirenz Concentration in Thai HIV-1 Patients. Pharmacogenomics and personalized medicine 14 (2021)
James Steven Leeder, Jean C Dinh, Andrea Gaedigk, Vincent S Staggs, Bhagwat Prasad, Robin E Pearce
Ontogeny of Scaling Factors for Pediatric PBPK Modeling and Simulation: Microsomal Protein Per Gram of Liver. Drug metabolism and disposition: the biological fate of chemicals (2021)
Daniel Carranza-Leon, Alyson L Dickson, Andrea Gaedigk, C Michael Stein, Cecilia P Chung
CYP2D6 genotype and reduced codeine analgesic effect in real-world clinical practice. The pharmacogenomics journal 21 (4) (2021)
Thuraya M Mutawi, Mohamed M Zedan, Raida S Yahya, Mahmoud M Zakaria, Mamdouh R El-Sawi, Andrea Gaedigk
Genetic variability of CYP2D6, CYP3A4 and CYP3A5 among the Egyptian population. Pharmacogenomics 22 (6) (2021)
Yaowaluck Hongkaew, Wendy Y Wang, Roger Gaedigk, Chonlaphat Sukasem, Andrea Gaedigk
Resolving discordant CYP2D6 genotyping results in Thai subjects: platform limitations and novel haplotypes. Pharmacogenomics 22 (9) (2021)
Monpat Chamnanphon, Sorawit Wainipitapong, Teeravut Wiwattarangkul, Phenphichcha Chuchuen, Kunathip Nissaipan, Weeraya Phaisal, Sookjaroen Tangwongchai, Chonlaphat Sukasem, Supeecha Wittayalertpanya, Andrea Gaedigk, Daruj Aniwattanapong, Pajaree Chariyavilaskul
CYP2D6 Predicts Plasma Donepezil Concentrations in a Cohort of Thai Patients with Mild to Moderate Dementia. Pharmacogenomics and personalized medicine 13 (2020)
Monpat Chamnanphon, Andrea Gaedigk, Apichaya Puangpetch, Ekawat Pasomsub, Wasun Chantratita, Rhea J Longley, Jetsumon Sattabongkot, Pajaree Chariyavilaskul, Chonlaphat Sukasem
Pharmacogene Variation in Thai Plasmodium vivax Relapse Patients Treated with a Combination of Primaquine and Chloroquine. Pharmacogenomics and personalized medicine 13 (2020)
Brian D Chapron, Jean C Dinh, Paul C Toren, Andrea Gaedigk, J Steven Leeder
The Respective Roles of CYP3A4 and CYP2D6 in the Metabolism of Pimozide to Established and Novel Metabolites. Drug metabolism and disposition: the biological fate of chemicals 48 (11) (2020)
Gregory McInnes, Rachel Dalton, Katrin Sangkuhl, Michelle Whirl-Carrillo, Seung-Been Lee, Philip S Tsao, Andrea Gaedigk, Russ B Altman, Erica L Woodahl
Transfer learning enables prediction of CYP2D6 haplotype function. PLoS computational biology 16 (11) (2020)
Charity Nofziger, Amy J Turner, Katrin Sangkuhl, Michelle Whirl-Carrillo, José A G Agúndez, John L Black, Henry M Dunnenberger, Gualberto Ruano, Martin Alexander Kennedy, Michael S Phillips, Houda Hachad, Teri E Klein, Andrea Gaedigk
PharmVar GeneFocus: CYP2D6. Clinical pharmacology and therapeutics 107 (1) (2019)
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Greyson P Twist, Teri E Klein, Neil A Miller, null null
The Evolution of PharmVar. Clinical pharmacology and therapeutics 105 (1) (2018)
Andrea Gaedigk, Jean C Dinh, Hyunyoung Jeong, Bhagwat Prasad, J Steven Leeder
Ten Years' Experience with the CYP2D6 Activity Score: A Perspective on Future Investigations to Improve Clinical Predictions for Precision Therapeutics. Journal of personalized medicine 8 (2) (2018)
Jun J Yang, Michelle Whirl-Carrillo, Stuart A Scott, Amy J Turner, Matthias Schwab, Yoichi Tanaka, Guilherme Suarez-Kurtz, Elke Schaeffeler, Teri E Klein, Neil A Miller, Andrea Gaedigk
Pharmacogene Variation Consortium Gene Introduction: NUDT15. Clinical pharmacology and therapeutics 105 (5) (2018)
Andrea Gaedigk, Katrin Sangkuhl, Michelle Whirl-Carrillo, Teri E Klein, James Steven Leeder
Prediction of CYP2D6 phenotype from genotype across world populations. Genetics in medicine : official journal of the American College of Medical Genetics 19 (1) (2016)