Clinical Significance of CLDN18.2 Expression in Metastatic Diffuse-Type Gastric Cancer.

Seo Ree Kim Kabsoo ShinJae Myung ParkHan-Hong Lee Kyo Young SongSung Hak LeeBohyun KimSang-Yeob Kim Junyoung SeoJeong-Oh KimSang-Young RohIn-Ho Kim

Published in: Journal of gastric cancer (2020)

CLDN18.2 expression was reduced in patients with PM but significantly intact in those with bone metastasis. Furthermore, CLDN18.2 expression was positively correlated with other adherens junction molecules, which is clinically associated with mDGC and PM pathogenesis.

Keyphrases

poor prognosis
particulate matter
air pollution
squamous cell carcinoma
binding protein
small cell lung cancer
heavy metals
low grade
bone mineral density