Weak immunohistochemical expression of galectin-3 near blisters in Hailey-Hailey disease.

Published in: Journal of cutaneous pathology (2021)

While the acantholysis process in HHD is related to abnormality in cadherin expression caused by altered Ca2+ pump concentration, lower expression of galectin-3 may cause the extension of blisters by initiating cell-to-cell disassembly in the epidermis.

Keyphrases

poor prognosis
single cell
binding protein
long non coding rna
cell adhesion