Hypermethylation of the miR-155 gene in the whole blood and decreased plasma level of miR-155 in rheumatoid arthritis.

Bogdan KolarzMarek CieslaMagdalena DryglewskaAnn K RosenthalMaria Majdan

Published in: PloS one (2020)

We show here higher miR-155 methylation in whole blood and lower plasma miR155 expression in RA patients in comparison to HC. The evaluation of miR-155 host gene methylation status or miR155 plasma level might be a potentially useful marker in RA determination.

Keyphrases

cell proliferation
long non coding rna
long noncoding rna
rheumatoid arthritis
poor prognosis
genome wide
dna methylation
end stage renal disease
disease activity
prognostic factors
high resolution
mass spectrometry