Scale up of rifapentine-isoniazid (3HP) for tuberculosis prevention amongst household contacts in two urban centers: An effectiveness assessment.

Hamidah HussainMaria JaswalSaira FarooqNauman SafdarFalak MadhaniShehla NooraniSheikh Shumail ShahbazNaseem SalahuddinFarhana AmanullahSaira KhowajaShadab ManzarJinsar Ali ShahZafar IslamAli Akber DahriMuddasser ShahzadSalmaan KeshavjeeMercedes C BecerraAamir J KhanAmyn Abdul Malik

Published in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)

We observed a high level of acceptance and completion of 3HP in programs implemented in two cities in Pakistan, with differences observed across the cities. These findings suggest that 3HP can be effectively scaled in urban settings to improve the reach and impact of TPT.

Keyphrases

mycobacterium tuberculosis
randomized controlled trial
systematic review
public health
hiv aids
emergency department
pulmonary tuberculosis
hepatitis c virus
antiretroviral therapy