Placental expression of asialoglycoprotein receptor associated with Hepatitis B virus transmission from mother to child.
Ashish Kumar VyasUsha RamakrishnaBijoya SenMojahidul IslamGayatri RamakrishnaSharda PatraArchana RastogiShiv Kumar SarinNirupama TrehanpatiPublished in: Liver international : official journal of the International Association for the Study of the Liver (2018)
This study revealed that increased expression of asialoglycoprotein receptor in placenta and colocalization with hepatitis B surface antigen strongly indicates its role in intrauterine transmission of hepatitis B virus. Asialoglycoprotein receptor-blocking strategy can be used for therapeutic intervention of vertical transmission.