In-vitro assessment of release of silicone oil droplets with the use of variety of syringes and needles used in intravitreal injections.
Natasha Ferreira Santos da CruzLydianne Lumack do Monte AgraChristine ProbstLuiz Henrique Soares Gonçalves de LimaJohn F CarpenterMauricio MaiaMichel Eid FarahGustavo Barreto MeloPublished in: European journal of ophthalmology (2021)
We found a high variability in SO content across syringes from the same lot. Additionally, there was no clear association between needle gauge and the number of SO particles, as well as their coefficient of variation. Finally, the needles accounted for a small number of SO particles in comparison to the combined syringe-needle setup.