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A single-dose, randomized crossover study in healthy Chinese subjects to evaluate pharmacokinetics and bioequivalence of two capsules of calcium dobesilate 0.5 g under fasting and fed conditions.

Yanmei LiuJie ChengLiyu LiangWeigang QianMeixian OuMengqi ZhangYijun WangYan WangKa PengJingying Jia
Published in: PloS one (2023)
In this study, the T calcium dobesilate 0.5 g capsule was bioequivalent to the reference product under both fasting and fed conditions. Taking food would slow down its rate and reduce its amount of absorption. Both formulations were generally well tolerated.
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