N-Acetyltransferase 10 Enhances Doxorubicin Resistance in Human Hepatocellular Carcinoma Cell Lines by Promoting the Epithelial-to-Mesenchymal Transition.

Xiuming ZhangJiang ChenShi JiangShilin HeYanfeng BaiLinghua ZhuRui Ma Xiao Liang

Published in: Oxidative medicine and cellular longevity (2019)

NAT10 may contribute to chemoresistance in HCC by regulating the EMT. The mechanism by which NAT10 regulates the EMT and doxorubicin sensitivity in HCC cells merits further investigation.

Keyphrases

epithelial mesenchymal transition
induced apoptosis
drug delivery
endothelial cells
cell cycle arrest
cancer therapy
signaling pathway
pluripotent stem cells
oxidative stress
cell death
pi k akt
cancer stem cells