Case report: Successful induction of buprenorphine/naloxone using a microdosing schedule and assertive outreach.
Jennifer RozyloKeren MitchellMohammadali NikooS Elise DuranteSkye P BarbicDaniel LinSteve MathiasPouya AzarPublished in: Addiction science & clinical practice (2020)
A microdosing schedule can be used to induce a patient onto buprenorphine/naloxone with no apparent withdrawal; gradually reducing illicit substance use. This case report builds on previous literature, highlighting ways to minimize barriers to induction of buprenorphine/naloxone, using a microdosing schedule and assertive outreach. Given the safety profile of buprenorphine and its potential to be a lifesaving intervention, a larger study of microdosing is indicated.