Prospective multicenter assessment of patient preferences for properties of gadolinium-based contrast media and their potential socioeconomic impact in a screening breast MRI setting.
Sean A WoolenJonathan P TroostShokoufeh KhalatbariAkshat C PujaraJennifer S McDonaldRobert J McDonaldPrasad ShankarAlana A LewinAmy N MelsaetherSteven M WestphalKatherine H PattersonAshley NettlesJohn P WelbyParth Pradip PatelNeud KirosLisa PiccoliMatthew S DavenportPublished in: European radiology (2021)
• Among women undergoing annual breast MRI screening, cancer detection sensitivity (attribute "importance," 44.3%) was valued more than GBCM-related risks (mild allergic reaction risk 19.5%, severe allergic reaction risk 17.0%, intracranial gadolinium retention 11.6%, out-of-pocket expense 7.5%). • Prospective four-center patient preference data have been incorporated into a GBCM choice simulator that allows users to input GBCM properties and calculate patient preference shares for competitor GBCMs. • Lower-income women placed more importance on out-of-pocket cost and less importance on cancer detection (p < 0.01) when prioritizing GBCM properties.
Keyphrases
- contrast enhanced
- case report
- papillary thyroid
- magnetic resonance imaging
- polycystic ovary syndrome
- squamous cell
- mental health
- label free
- type diabetes
- pregnancy outcomes
- squamous cell carcinoma
- clinical trial
- early onset
- insulin resistance
- metabolic syndrome
- breast cancer risk
- real time pcr
- human health
- skeletal muscle
- cross sectional
- deep learning
- data analysis
- drug induced
- double blind
- childhood cancer
- virtual reality