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Prospective multicenter assessment of patient preferences for properties of gadolinium-based contrast media and their potential socioeconomic impact in a screening breast MRI setting.

Sean A WoolenJonathan P TroostShokoufeh KhalatbariAkshat C PujaraJennifer S McDonaldRobert J McDonaldPrasad ShankarAlana A LewinAmy N MelsaetherSteven M WestphalKatherine H PattersonAshley NettlesJohn P WelbyParth Pradip PatelNeud KirosLisa PiccoliMatthew S Davenport
Published in: European radiology (2021)
• Among women undergoing annual breast MRI screening, cancer detection sensitivity (attribute "importance," 44.3%) was valued more than GBCM-related risks (mild allergic reaction risk 19.5%, severe allergic reaction risk 17.0%, intracranial gadolinium retention 11.6%, out-of-pocket expense 7.5%). • Prospective four-center patient preference data have been incorporated into a GBCM choice simulator that allows users to input GBCM properties and calculate patient preference shares for competitor GBCMs. • Lower-income women placed more importance on out-of-pocket cost and less importance on cancer detection (p < 0.01) when prioritizing GBCM properties.
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