Utilizing Human-Induced Pluripotent Stem Cells to Study Cardiac Electroporation Pulsed-Field Ablation.

Leonid Maizels Eyal HellerMichal LandesbergShany GlatsteinIrit HuberGil ArbelAmira GepsteinDoron AronsonShirley SharabiRoy BeinartAmit SegevElad Maor Lior Gepstein

Published in: Circulation. Arrhythmia and electrophysiology (2024)

Cardiac electroporation may be studied utilizing hiPSC-derived cardiac tissue, whereas providing novel insights into PFA temporal and electrophysiological characteristics, facilitating electroporation protocol optimization, screening for potential PFA-sensitizers, and investigating the mechanistic nature of PFA antiarrhythmic properties.

Keyphrases

induced pluripotent stem cells
left ventricular
endothelial cells
randomized controlled trial
risk assessment
catheter ablation
atrial fibrillation
human health
climate change
solar cells