Time restricted feeding and mental health: a review of possible mechanisms on affective and cognitive disorders.
Walter CurrentiJustyna GodosSabrina CastellanoMaria Paola MogaveroRaffaele FerriFilippo CaraciGiuseppe GrossoFabio GalvanoPublished in: International journal of food sciences and nutrition (2020)
In the last decades, a high increase in life expectancy not adequately balanced by an improvement in the quality of life has been observed, leading possibly to an increase in the prevalence of affective and cognitive disorders related to aging, such as depression, cognitive impairment, dementia and Alzheimer's disease. As mental illnesses have multifactorial aetiologies, many modifiable factors including lifestyle and nutrition play an essential role. Among nutritional factors, intermittent fasting has emerged as an innovative strategy to prevent and treat mental health disorders, sleep disturbances and cognitive impairment. Among all types of intermittent fasting regimens, the time restricted feeding appears to be the most promising protocol as it allows to induce benefits of a total fasting without reducing global calories and nutrients intake. This review summarises the evidence on the effect of time restricted feeding towards brain health, emphasising its role on brain signalling, neurogenesis and synaptic plasticity.
Keyphrases
- mental health
- cognitive impairment
- blood glucose
- physical activity
- insulin resistance
- white matter
- mental illness
- bipolar disorder
- resting state
- sleep quality
- healthcare
- cerebral ischemia
- public health
- metabolic syndrome
- depressive symptoms
- randomized controlled trial
- high intensity
- cardiovascular disease
- weight loss
- heavy metals
- mild cognitive impairment
- risk factors
- risk assessment
- type diabetes
- blood pressure
- body mass index
- weight gain
- glycemic control