In vitro effect of granulocyte-macrophage colony-stimulating factor (GM-CSF) on the expression of genes related to sperm motility and energy metabolism and intracytoplasmic sperm injection outcomes in obstructive azoospermic patients.

Samaneh Aghajanpour Elham Hosseini Fatemeh Sadat Amjadi Masoud Mohammadian Zahra Zandieh Farnaz Mohammadian Raheleh Kafaeinezhad Mahnaz Ashrafi

Published in: Molecular biology reports (2024)

GM-CSF increased the expression of genes related to motility and the energy metabolism pathway and effectively promoted the motility of testis-extracted spermatozoa, consequently yielding positive clinical outcomes.

Keyphrases

poor prognosis
biofilm formation
end stage renal disease
genome wide
ejection fraction
newly diagnosed
chronic kidney disease
binding protein
peritoneal dialysis
adipose tissue
bioinformatics analysis
escherichia coli
staphylococcus aureus
gene expression
skeletal muscle
dna methylation
patient reported outcomes