Metered-dose inhalers versus nebulization for the delivery of albuterol for acute exacerbations of wheezing or asthma in children: A systematic review with meta-analysis.
Laura Payares-SalamancaSandra Contreras-ArrietaVictor Florez-GarcíaAlexander Barrios-SanjuaneloIvan Stand-NiñoCarlos E Rodriguez-MartinezPublished in: Pediatric pulmonology (2020)
This review, an update of a previously-published meta-analysis, showed a significant reduction in the PIS and a significantly smaller increase in HR when albuterol was delivered through MDI+S than when it was delivered through NEB.