Optimization of parathyroid 11C-choline PET protocol for localization of parathyroid adenomas in patients with primary hyperparathyroidism.

Milou E NoltesSchelto KruijffWalter NoordzijEef D TelengaDavid Vállez GarcíaMalgorzata Trofimiuk-MüldnerMarta OpalińskaAlicja Hubalewska-DydejczykGert LuurtsemaRudi A J O DierckxMostafa El MoumniRonald BoellaardAdrienne H Brouwers

Published in: EJNMMI research (2019)

The optimal time to start PET/CT scanning in patients with pHPT is 20 min after mean injection of 6.3 MBq/kg 11C-choline, with a recommended scan duration of at least 5 min. Alternatively, the radioactivity dose can be lowered by 50% while keeping a 10-min scan duration without losing the accuracy of 11C-choline PET/CT interpretation.

Keyphrases

pet ct
computed tomography
positron emission tomography
randomized controlled trial
high resolution
ultrasound guided
magnetic resonance
mass spectrometry
electron microscopy