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Association Between Biomarkers and Clinical Outcomes of Pembrolizumab Monotherapy in Patients With Metastatic Triple-Negative Breast Cancer: KEYNOTE-086 Exploratory Analysis.

Sherene LoiRoberto SalgadoThomas PowlesJavier CortesDavid W CesconEric P WinerDeborah L ToppmeyerHope S RugoMichelino De LaurentiisRita NandaHiroji IwataAhmad AwadaAntoinette R TanYuan SunVassiliki KarantzaAnran WangLingkang HuangAssieh SaadatpourRazvan CristescuJennifer YearleyJared LuncefordPetar JelinicSylvia Adams
Published in: JCO precision oncology (2023)
GEP were associated with improved clinical outcomes of pembrolizumab and may help identify patients with mTNBC who are most likely to respond to pembrolizumab monotherapy.
Keyphrases
  • advanced non small cell lung cancer
  • combination therapy
  • open label
  • epidermal growth factor receptor
  • randomized controlled trial
  • clinical trial