Association Between Biomarkers and Clinical Outcomes of Pembrolizumab Monotherapy in Patients With Metastatic Triple-Negative Breast Cancer: KEYNOTE-086 Exploratory Analysis.
Sherene LoiRoberto SalgadoThomas PowlesJavier CortesDavid W CesconEric P WinerDeborah L ToppmeyerHope S RugoMichelino De LaurentiisRita NandaHiroji IwataAhmad AwadaAntoinette R TanYuan SunVassiliki KarantzaAnran WangLingkang HuangAssieh SaadatpourRazvan CristescuJennifer YearleyJared LuncefordPetar JelinicSylvia AdamsPublished in: JCO precision oncology (2023)
GEP were associated with improved clinical outcomes of pembrolizumab and may help identify patients with mTNBC who are most likely to respond to pembrolizumab monotherapy.