Preservative-Free versus Benzalkonium Chloride-Preserved Latanoprost Ophthalmic Solution in Patients with Primary Open-Angle Glaucoma or Ocular Hypertension: A Phase 3 US Clinical Trial.
Jason BacharachIqbal Ike K AhmedElizabeth D SharpeMichael S KorenfeldSteven ZhangChristophe BaudouinPublished in: Clinical ophthalmology (Auckland, N.Z.) (2023)
In patients with POAG or OHT, both T2345 and BPL maintained IOP at or below clinically meaningful values for the duration of the study. T2345 showed a favorable safety profile, with numerically lower incidences of ocular TEAEs than BPL.