Inter-fraction dynamics during post-operative 5 fraction cavity hypofractionated stereotactic radiotherapy with a MR LINAC: a prospective serial imaging study.
Hendrick TanJames StewartMark RuschinMichael H WangSten MyrehaugChia-Lin TsengJay DetskyZain HusainHanbo ChenArjun SahgalHany SolimanPublished in: Journal of neuro-oncology (2022)
Statistically significant reductions in cavity CTV was observed during HSRT, supporting the use of MR image guided radiation therapy and treatment adaptation to mitigate toxicity. Significant CTV contouring variability was seen between T1c and T2f sequences. Trial registration NCT04075305 - August 30, 2019.
Keyphrases
- radiation therapy
- locally advanced
- radiation induced
- magnetic resonance
- contrast enhanced
- high resolution
- early stage
- clinical trial
- study protocol
- weight loss
- oxidative stress
- brain metastases
- phase iii
- randomized controlled trial
- squamous cell carcinoma
- small cell lung cancer
- photodynamic therapy
- oxide nanoparticles