Expression of antimicrobial peptides in the amniotic fluid of women with cervical insufficiency.
Youngmi KimKeun-Young LeeJae Jun LeeHyunjin TakSung-Taek ParkJi-Eun SongGa-Hyun SonPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2022)
Amniotic fluid HNP-3 and hBD-2 levels increased in women with CI compared with normal controls. Moreover, increased amniotic fluid hBD-2 levels mid-pregnancy were associated with favorable pregnancy outcomes in women with CI. AMPs in the amniotic fluid may participate in host defense against ascending infection in women with CI.