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The 3D Genome Browser: a web-based browser for visualizing 3D genome organization and long-range chromatin interactions.

Yanli WangFan SongBo ZhangLijun ZhangJie XuDa KuangDaofeng LiMayank N K ChoudharyYun LiMing HuRoss HardisonTing WangFeng Yue
Published in: Genome biology (2018)
Here, we introduce the 3D Genome Browser, http://3dgenome.org , which allows users to conveniently explore both their own and over 300 publicly available chromatin interaction data of different types. We design a new binary data format for Hi-C data that reduces the file size by at least a magnitude and allows users to visualize chromatin interactions over millions of base pairs within seconds. Our browser provides multiple methods linking distal cis-regulatory elements with their potential target genes. Users can seamlessly integrate thousands of other omics data to gain a comprehensive view of both regulatory landscape and 3D genome structure.
Keyphrases
  • genome wide
  • transcription factor
  • electronic health record
  • gene expression
  • big data
  • dna damage
  • dna methylation
  • machine learning