Cross-sectional associations of sex hormones with leucocyte telomere length, a marker of biological age, in a community-based cohort of older men.
Bu B YeapJennie HuiMatthew W KnuimanDavid J HandelsmanLeon FlickerMark L DivitiniGillian M ArscottSusan V McLennanStephen M TwiggOsvaldo P AlmeidaGraeme J HankeyJonathan GolledgePaul E NormanJohn P BeilbyPublished in: Clinical endocrinology (2019)
In older men, neither T nor DHT is associated with LTL while E2 is independently associated with LTL and SHBG is inversely associated, thus relating sex hormone exposure to lower biological age. Further research is needed to determine causality and clarify the role of sex hormones in male ageing.