LncRNA MYLK-AS1 facilitates tumor progression and angiogenesis by targeting miR-424-5p/E2F7 axis and activating VEGFR-2 signaling pathway in hepatocellular carcinoma.

Fei TengJu-Xiang ZhangQi-Meng ChangXu-Bo WuWei-Guo TangJian-Fa WangJin-Feng FengZi-Ping ZhangZhi-Qiu Hu

Published in: Journal of experimental & clinical cancer research : CR (2020)

MYLK-AS1 and E2F7 are closely related to some malignant clinicopathological features and prognosis of HCC, thus the MYLK-AS1/ miR-424-5p/E2F7 signaling pathway might represent a promising treatment strategy to combat HCC.

Keyphrases

signaling pathway
pi k akt
epithelial mesenchymal transition
induced apoptosis
vascular endothelial growth factor
poor prognosis
endothelial cells
long non coding rna
cell proliferation
endoplasmic reticulum stress
drug induced