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Determinants of attained estradiol levels in response to oral estradiol plus progesterone therapy.

Intira SriprasertH N HodisB BernickS MirkinW J Mack
Published in: Climacteric : the journal of the International Menopause Society (2020)
Adjusting for E2 dose and baseline E2 level, on-trial E2 levels were significantly associated with time since menopause, current smoking, and current alcohol use. Practitioners should consider these factors in individual women to achieve a desirable E2 level during HT.
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