Persistent depressive symptoms are associated with frontal regional atrophy in patients with Alzheimer's disease.

Lindsey Isla SinclairClive G Ballardnull null

Published in: International journal of geriatric psychiatry (2022)

We have found mixed evidence of increased regional atrophy in depression in AD, mainly in frontal brain regions. We found no evidence to support a vascular basis for depression in AD.

Keyphrases

depressive symptoms
sleep quality
social support
functional connectivity
working memory
cognitive decline
cerebral ischemia
mild cognitive impairment
subarachnoid hemorrhage