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Persistent depressive symptoms are associated with frontal regional atrophy in patients with Alzheimer's disease.

Lindsey Isla SinclairClive G Ballardnull null
Published in: International journal of geriatric psychiatry (2022)
We have found mixed evidence of increased regional atrophy in depression in AD, mainly in frontal brain regions. We found no evidence to support a vascular basis for depression in AD.
Keyphrases
  • depressive symptoms
  • sleep quality
  • social support
  • functional connectivity
  • working memory
  • cognitive decline
  • cerebral ischemia
  • mild cognitive impairment
  • subarachnoid hemorrhage