Effect of Sitagliptin on Islet Function in Pancreatic Insufficient Cystic Fibrosis With Abnormal Glucose Tolerance.

Andrea KellySaba SheikhDarko StefanovskiAmy J PeleckisSarah C NyirjesyJack N EielAniket SidhayeRussell LocalioRobert GallopDiva D De LeonDenis HadjiliadisRonald C RubensteinMichael R Rickels

Published in: The Journal of clinical endocrinology and metabolism (2021)

In glucose intolerant PI-CF, sitagliptin intervention augmented meal-related incretin responses with improved early insulin secretion and glucagon suppression without affecting postprandial glycemia.

Keyphrases

cystic fibrosis
blood glucose
pseudomonas aeruginosa
randomized controlled trial
lung function
type diabetes
blood pressure
metabolic syndrome
insulin resistance
adipose tissue
skeletal muscle
drug induced
air pollution