How is quality of life defined and assessed in published research?

Daniel S J CostaRebecca Mercieca-BebberClaudia RutherfordMargaret-Ann TaitMadeleine T King

Published in: Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation (2021)

These results demonstrate considerable heterogeneity in the definition and operationalisation of (HR)QOL, between and within studies. This limits meaningful interpretation of (HR)QOL scores and complicates literature searches. Investigators should define constructs and select instruments aligned with their definitions.

Keyphrases

systematic review
single cell
case control
patient reported outcomes
randomized controlled trial
meta analyses