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Faecal Metabolomics in Paediatric Inflammatory Bowel Disease: A Systematic Review.

Jasmijn Z JagtCharlotte M VerburgtRalph de VriesNanne K H de BoerMarc A BenningaWouter J de JongeJohan E van LimbergenTim G J de Meij
Published in: Journal of Crohn's & colitis (2022)
This systematic review provides evidence for distinct faecal metabolomic profiles in paediatric IBD. However, results varied across studies, possibly due to differences in study design and applied analytical techniques. Faecal metabolomics could provide more insight into host-microbial interactions in IBD, but further studies with standardized methodologies and reporting are needed.
Keyphrases
  • systematic review
  • mass spectrometry
  • intensive care unit
  • emergency department
  • case control
  • ulcerative colitis
  • meta analyses
  • microbial community
  • liquid chromatography
  • randomized controlled trial