scMuffin: an R package to disentangle solid tumor heterogeneity by single-cell gene expression analysis.

Valentina NaleAlice ChiodiNoemi Di NanniIngrid CifolaMarco MoscatelliCinzia CocolaMatteo GnocchiEleonora PiscitelliAda SulaIleana ZucchiRolland ReinboldLuciano MilanesiAlessandra MezzelaniParide PelucchiEttore Mosca

Published in: BMC bioinformatics (2023)

The analyses offered by scMuffin and the results achieved in the case study show that our tool helps addressing the main challenges in the bioinformatics analysis of SC expression data from solid tumors.

Keyphrases

single cell
genome wide identification
rna seq
poor prognosis
high throughput
electronic health record
copy number
genome wide
big data
transcription factor
binding protein
long non coding rna
artificial intelligence
data analysis
deep learning