Can 18F-FDG PET/CT predict EGFR status in patients with non-small cell lung cancer? A systematic review and meta-analysis.

Bulin DuShu WangYan CuiGuanghui LiuXuena LiYaming Li

Published in: BMJ open (2021)

Meta-analysis results showed 18F-FDG PET/CT had low pooled sensitivity and specificity. The low DOR and the likelihood ratio scatter plot indicated that 18F-FDG PET/CT should be used with caution when predicting EGFR mutations in patients with NSCLC.

Keyphrases

small cell lung cancer
systematic review
epidermal growth factor receptor
tyrosine kinase
advanced non small cell lung cancer
brain metastases
meta analyses
randomized controlled trial
study protocol
case control